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Use of knowledge-based restraints in phenix.refine to improve macromolecular refinement at low resolution
Traditional methods for macromolecular refinement often have limited success at low resolution (3.0–3.5 Å or worse), producing models that score poorly on crystallographic and geometric validation criteria. To improve low-resolution refinement, knowledge from macromolecular chemistry and homology wa...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322597/ https://ncbi.nlm.nih.gov/pubmed/22505258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444911047834 |
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