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Cloning, expression, purification, crystallization and preliminary crystallographic analysis of the C-terminal domain of Par-4 (PAWR)

Prostate apoptosis response-4 protein is an intrinsically disordered pro-apoptotic protein with tumour suppressor function. Par-4 is known for its selective induction of apoptosis in cancer cells only and its ability to interact with various apoptotic proteins via its C-terminus. Par-4, with its uni...

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Библиографические подробности
Главные авторы: Tiruttani Subhramanyam, Udaya Kumar, Kubicek, Jan, Eidhoff, Ulf B., Labahn, Joerg
Формат: Artigo
Язык:Inglês
Опубликовано: International Union of Crystallography 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157423/
https://ncbi.nlm.nih.gov/pubmed/25195896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14014691
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