Imaging Activity in Neurons and Glia with a Polr2a-based and Cre-dependent GCaMP5G-IRES-tdTomato Reporter Mouse

New strategies for introducing genetically encoded activity indicators into animal models facilitate the investigation of nervous system function. We have developed the PC::G5-tdT mouse line that expresses the GCaMP5G calcium indicator in a Cre-dependent fashion. Instead of targeting the ROSA26 locu...

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Detalles Bibliográficos
Autores principales: Gee, J. Michael, Smith, Nathan A., Fernandez, Fernando R., Economo, Michael N., Brunert, Daniela, Rothermel, Markus, Morris, S. Craig, Talbot, Amy, Palumbos, Sierra, Ichida, Jennifer M., Shepherd, Jason D., West, Peter J., Wachowiak, Matt, Capecchi, Mario R., Wilcox, Karen S., White, John A., Tvrdik, Petr
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156920/
https://ncbi.nlm.nih.gov/pubmed/25155958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.07.024
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