Imaging Activity in Neurons and Glia with a Polr2a-based and Cre-dependent GCaMP5G-IRES-tdTomato Reporter Mouse

New strategies for introducing genetically encoded activity indicators into animal models facilitate the investigation of nervous system function. We have developed the PC::G5-tdT mouse line that expresses the GCaMP5G calcium indicator in a Cre-dependent fashion. Instead of targeting the ROSA26 locu...

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Detalhes bibliográficos
Main Authors: Gee, J. Michael, Smith, Nathan A., Fernandez, Fernando R., Economo, Michael N., Brunert, Daniela, Rothermel, Markus, Morris, S. Craig, Talbot, Amy, Palumbos, Sierra, Ichida, Jennifer M., Shepherd, Jason D., West, Peter J., Wachowiak, Matt, Capecchi, Mario R., Wilcox, Karen S., White, John A., Tvrdik, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156920/
https://ncbi.nlm.nih.gov/pubmed/25155958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.07.024
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