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Neutral Polymer Micelle Carriers with pH-Responsive, Endosome-Releasing Activity Modulate Antigen Trafficking to Enhance CD8 T-Cell Responses
Synthetic subunit vaccines need to induce CD8(+) cytotoxic T-cell (CTL) responses for effective vaccination against intracellular pathogens. Most subunit vaccines primarily generate humoral immune responses, with a weaker than desired CD8(+) cytotoxic T-cell response. Here, a neutral, pH-responsive...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156909/ https://ncbi.nlm.nih.gov/pubmed/24698946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.03.041 |
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