Modulating Hydrogel Crosslink Density and Degradation to Control Bone Morphogenetic Protein Delivery and In Vivo Bone Formation

Bone morphogenetic proteins (BMPs) show promise in therapies for improving bone formation after injury; however, the high supraphysiological concentrations required for desired osteoinductive effects, off-target concerns, costs, and patient variability have limited the use of BMP-based therapeutics....

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Hlavní autoři: Holloway, Julianne L., Ma, Henry, Rai, Reena, Burdick, Jason A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156908/
https://ncbi.nlm.nih.gov/pubmed/24905414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.05.053
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