Delivery of the Immunosuppressive Antigen Salp15 to Antigen-Presenting Cells by Salmonella enterica Serovar Typhimurium aroA Mutants

A Salmonella enterica serovar Typhimurium aroA-deficient delivery system was used to target the immunosuppressive protein Salp15 to antigen-presenting cells. In vitro and in vivo infections with Salp15-containing Salmonella resulted in an impaired CD4(+)-T-cell activation, suggesting that the protei...

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Autori principali: Motameni, Amir-Reza T., Juncadella, Ignacio J., Ananthanarayanan, Shobana K., Hedrick, Michael N., Huet-Hudson, Yvette, Anguita, Juan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC415690/
https://ncbi.nlm.nih.gov/pubmed/15155675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3638-3642.2004
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