Delivery of the Immunosuppressive Antigen Salp15 to Antigen-Presenting Cells by Salmonella enterica Serovar Typhimurium aroA Mutants

A Salmonella enterica serovar Typhimurium aroA-deficient delivery system was used to target the immunosuppressive protein Salp15 to antigen-presenting cells. In vitro and in vivo infections with Salp15-containing Salmonella resulted in an impaired CD4(+)-T-cell activation, suggesting that the protei...

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Publicat a:Infect Immun
Autors principals: Motameni, Amir-Reza T., Juncadella, Ignacio J., Ananthanarayanan, Shobana K., Hedrick, Michael N., Huet-Hudson, Yvette, Anguita, Juan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2004
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415690/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15155675/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.6.3638-3642.2004
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