8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and α-smooth muscle actin polymerization

Reactive oxygen species (ROS) are activators of cell signaling and modify cellular molecules, including DNA. 8-Oxo-7,8-dihydroguanine (8-oxoG) is one of the prominent lesions in oxidatively damaged DNA, whose accumulation is causally linked to various diseases and aging processes, whereas its etiolo...

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Autors principals: Luo, Jixian, Hosoki, Koa, Bacsi, Attila, Radak, Zsolt, Hegde, Muralidhar L., Sur, Sanjiv, Hazra, Tapas K., Brasier, Allan R., Ba, Xueqing, Boldogh, Istvan
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156873/
https://ncbi.nlm.nih.gov/pubmed/24681335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.03.030
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