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Fibril Elongation by Aβ(17–42): Kinetic Network Analysis of Hybrid-Resolution Molecular Dynamics Simulations

[Image: see text] A critical step of β-amyloid fibril formation is fibril elongation in which amyloid-β monomers undergo structural transitions to fibrillar structures upon their binding to fibril tips. The atomic detail of the structural transitions remains poorly understood. Computational characte...

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Detalhes bibliográficos
Main Authors: Han, Wei, Schulten, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156860/
https://ncbi.nlm.nih.gov/pubmed/25134066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja507002p
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