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Atomic Resolution Structure of Monomorphic Aβ(42) Amyloid Fibrils
Amyloid-β (Aβ) is a 39–42 residue protein produced by the cleavage of the amyloid precursor protein (APP), which subsequently aggregates to form cross-β amyloid fibrils that are a hallmark of Alzheimer’s disease (AD). The most prominent forms of Aβ are Aβ(1–40) and Aβ(1–42), which differ by two amin...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389415/ https://ncbi.nlm.nih.gov/pubmed/27355699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b05129 |
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