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Amyloid-Associated Activity Contributes to the Severity and Toxicity of a Prion Phenotype

The self-assembly of alternative conformations of normal proteins into amyloid aggregates has been implicated in both the acquisition of new functions and in the appearance and progression of disease. However, while these amyloidogenic pathways are linked to the emergence of new phenotypes, numerous...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pezza, John A., Villali, Janice, Sindi, Suzanne S., Serio, Tricia R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156856/
https://ncbi.nlm.nih.gov/pubmed/25023996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5384
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