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Experimental basis for a new allosteric model for multisubunit proteins
Monod, Wyman, and Changeux (MWC) explained allostery in multisubunit proteins with a widely applied theoretical model in which binding of small molecules, so-called allosteric effectors, affects reactivity by altering the equilibrium between more reactive (R) and less reactive (T) quaternary structu...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156698/ https://ncbi.nlm.nih.gov/pubmed/25139985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413566111 |
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