GlialCAM, a CLC-2 Cl(-) Channel Subunit, Activates the Slow Gate of CLC Chloride Channels

GlialCAM, a glial cell adhesion molecule mutated in megalencephalic leukoencephalopathy with subcortical cysts, targets the CLC-2 Cl(-) channel to cell contacts in glia and activates CLC-2 currents in vitro and in vivo. We found that GlialCAM clusters all CLC channels at cell contacts in vitro and t...

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Bibliografische gegevens
Hoofdauteurs: Jeworutzki, Elena, Lagostena, Laura, Elorza-Vidal, Xabier, López-Hernández, Tania, Estévez, Raúl, Pusch, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2014
Onderwerpen:
Channels and Transporters
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156679/
https://ncbi.nlm.nih.gov/pubmed/25185546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.040
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