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Replication competent virus as an important source of bias in HIV latency models utilizing single round viral constructs
The central memory T cell (TCM) model forms a unique HIV-1 latency model based on primary cells that closely resemble in vivo TCM. The virus employed in this model is based on an engineered vector incapable of replication after initial infection. We show that despite this strategy, replication compe...
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| Główni autorzy: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156640/ https://ncbi.nlm.nih.gov/pubmed/25142072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0070-3 |
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