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Experimental Pneumococcal Meningitis: Impaired Clearance of Bacteria from the Blood Due to Increased Apoptosis in the Spleen in Bcl-2-Deficient Mice
Necrotic and apoptotic neuronal cell death can be found in pneumococcal meningitis. We investigated the role of Bcl-2 as an antiapoptotic gene product in pneumococcal meningitis using Bcl-2 knockout (Bcl-2(−/−)) mice. By using a model of pneumococcal meningitis induced by intracerebral infection, Bc...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC415656/ https://ncbi.nlm.nih.gov/pubmed/15155612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3113-3119.2004 |
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