Experimental Pneumococcal Meningitis: Impaired Clearance of Bacteria from the Blood Due to Increased Apoptosis in the Spleen in Bcl-2-Deficient Mice

Necrotic and apoptotic neuronal cell death can be found in pneumococcal meningitis. We investigated the role of Bcl-2 as an antiapoptotic gene product in pneumococcal meningitis using Bcl-2 knockout (Bcl-2(−/−)) mice. By using a model of pneumococcal meningitis induced by intracerebral infection, Bc...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Wellmer, Andreas, von Mering, Matthias, Spreer, Annette, Diem, Ricarda, Eiffert, Helmut, Noeske, Christiane, Bunkowski, Stefanie, Gold, Ralf, Nau, Roland
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC415656/
https://ncbi.nlm.nih.gov/pubmed/15155612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3113-3119.2004
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky