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Two splicing factors carrying serine-arginine motifs, TSR1 and TSR1IP, regulate splicing, mRNA stability, and rRNA processing in Trypanosoma brucei

In trypanosomes, mRNAs are processed by trans-splicing; in this process, a common exon, the spliced leader, is added to all mRNAs from a small RNA donor, the spliced leader RNA (SL RNA). However, little is known regarding how this process is regulated. In this study, we investigated the function of...

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Autors principals: Gupta, Sachin Kumar, Chikne, Vaibhav, Eliaz, Dror, Tkacz, Itai Dov, Naboishchikov, Ilana, Carmi, Shai, Waldman Ben-Asher, Hiba, Michaeli, Shulamit
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156503/
https://ncbi.nlm.nih.gov/pubmed/24922194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.29143
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