Basal Splicing Factors Regulate the Stability of Mature mRNAs in Trypanosomes

Gene expression in trypanosomes is mainly regulated post-transcriptionally. Genes are transcribed as polycistronic mRNAs that are dissected by the concerted action of trans-splicing and polyadenylation. In trans-splicing, a common exon, the spliced leader, is added to all mRNAs from a small RNA. In...

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Bibliographic Details
Main Authors: Gupta, Sachin Kumar, Carmi, Shai, Ben-Asher, Hiba Waldman, Tkacz, Itai Dov, Naboishchikov, Ilana, Michaeli, Shulamit
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576102/
https://ncbi.nlm.nih.gov/pubmed/23283975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.416578
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