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Trypanosome Spliced-Leader-Associated RNA (SLA1) Localization and Implications for Spliced-Leader RNA Biogenesis

Spliced-leader-associated RNA (SLA1) guides the pseudouridylation at position −12 (relative to the 5′ splice site) of the spliced-leader (SL) RNA in all trypanosomatid species. Nevertheless, the exact role of this RNA is currently unknown. Here, we demonstrate that the absence of pseudouridine on Le...

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Detalhes bibliográficos
Main Authors: Hury, Avraham, Goldshmidt, Hanoch, Tkacz, Itai Dov, Michaeli, Shulamit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620742/
https://ncbi.nlm.nih.gov/pubmed/19028994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00322-08
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