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Persistent ER Stress Induces the Spliced Leader RNA Silencing Pathway (SLS), Leading to Programmed Cell Death in Trypanosoma brucei

Trypanosomes are parasites that cycle between the insect host (procyclic form) and mammalian host (bloodstream form). These parasites lack conventional transcription regulation, including factors that induce the unfolded protein response (UPR). However, they possess a stress response mechanism, the...

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Bibliografische gegevens
Hoofdauteurs: Goldshmidt, Hanoch, Matas, Devorah, Kabi, Anat, Carmi, Shai, Hope, Ronen, Michaeli, Shulamit
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809764/
https://ncbi.nlm.nih.gov/pubmed/20107599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000731
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