Analysis of Spliceosomal Proteins in Trypanosomatids Reveals Novel Functions in mRNA Processing

In trypanosomatids, all mRNAs are processed via trans-splicing, although cis-splicing also occurs. In trans-splicing, a common small exon, the spliced leader (SL), which is derived from a small SL RNA species, is added to all mRNAs. Sm and Lsm proteins are core proteins that bind to U snRNAs and are...

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Main Authors: Tkacz, Itai Dov, Gupta, Sachin Kumar, Volkov, Vadim, Romano, Mali, Haham, Tomer, Tulinski, Pawel, Lebenthal, Ilana, Michaeli, Shulamit
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934664/
https://ncbi.nlm.nih.gov/pubmed/20592024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095349
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