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DNA Methylation Is Dispensable for Suppression of the Agouti viable yellow Controlling Element in Murine Embryonic Stem Cells

The agouti viable (A(vy)) locus is considered a model to understand how retroelements function as controlling elements in mammals. Epigenetic factors, principally CpG methylation, are widely held to play a dominant regulatory role in controlling the locus' activity. The purpose of this study wa...

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Hlavní autoři: Stathopoulou, Athanasia, Lucchiari, Giulia, Ooi, Steen K. T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156423/
https://ncbi.nlm.nih.gov/pubmed/25191835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107355
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