Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BRCT domains of Rad4(TOPBP1)

To gain insight into the function and organization of proteins assembled on the DNA in response to genotoxic insult we investigated the phosphorylation of the Schizosaccharomyces pombe PCNA-like checkpoint protein Rad9. C-terminal T412/S423 phosphorylation of Rad9 by Rad3(ATR) occurs in S phase with...

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Bibliographische Detailangaben
Hauptverfasser: Furuya, Kanji, Poitelea, Marius, Guo, Liandi, Caspari, Thomas, Carr, Antony M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2004
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC415640/
https://ncbi.nlm.nih.gov/pubmed/15155581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.291104
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