Učitavanje...
Phosphorylation-dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4(TopBP1)
The BRCT-domain protein, Rad4(TopBP1), facilitates activation of the DNA damage checkpoint in S. pombe by physically coupling the Rad9-Rad1-Hus1 clamp, the Rad3(ATR)-Rad26(ATRIP) kinase complex and Crb2(53BP1) mediator. We have now determined crystal structures of the BRCT repeats of Rad4(TopBP1), r...
Spremljeno u:
| Izdano u: | Mol Cell |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4944838/ https://ncbi.nlm.nih.gov/pubmed/24074952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.08.030 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|