Pharmacokinetics and Safety of Intravenous Voriconazole in Children after Single- or Multiple-Dose Administration

We conducted a multicenter study of the safety, tolerability, and plasma pharmacokinetics of the parenteral formulation of voriconazole in immunocompromised pediatric patients (2 to 11 years old). Single doses of 3 or 4 mg/kg of body weight were administered to six and five children, respectively. I...

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Autori principali: Walsh, Thomas J., Karlsson, Mats O., Driscoll, Timothy, Arguedas, Adriano G., Adamson, Peter, Saez-Llorens, Xavier, Vora, Ajay J., Arrieta, Antonio C., Blumer, Jeffrey, Lutsar, Irja, Milligan, Peter, Wood, Nolan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Clinical Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC415618/
https://ncbi.nlm.nih.gov/pubmed/15155217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2166-2172.2004
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