Comparison of Pharmacokinetics and Safety of Voriconazole Intravenous-to-Oral Switch in Immunocompromised Children and Healthy Adults

Voriconazole pharmacokinetics are not well characterized in children despite prior studies. To assess the appropriate pediatric dosing, a study was conducted in 40 immunocompromised children aged 2 to <12 years to evaluate the pharmacokinetics and safety of voriconazole following intravenous (IV)...

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Autors principals: Driscoll, Timothy A., Yu, Lolie C., Frangoul, Haydar, Krance, Robert A., Nemecek, Eneida, Blumer, Jeffrey, Arrieta, Antonio, Graham, Michael L., Bradfield, Scott M., Baruch, Alice, Liu, Ping
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232783/
https://ncbi.nlm.nih.gov/pubmed/21968355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00531-11
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