Comparison of Pharmacokinetics and Safety of Voriconazole Intravenous-to-Oral Switch in Immunocompromised Adolescents and Healthy Adults

The current voriconazole dosing recommendation in adolescents is based on limited efficacy and pharmacokinetic data. To confirm the appropriateness of dosing adolescents like adults, a pharmacokinetic study was conducted in 26 immunocompromised adolescents aged 12 to <17 years following intraveno...

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Autores principales: Driscoll, Timothy A., Frangoul, Haydar, Nemecek, Eneida R., Murphey, Donald K., Yu, Lolie C., Blumer, Jeffrey, Krance, Robert A., Baruch, Alice, Liu, Ping
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232803/
https://ncbi.nlm.nih.gov/pubmed/21911570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05010-11
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