Comparison of Pharmacokinetics and Safety of Voriconazole Intravenous-to-Oral Switch in Immunocompromised Adolescents and Healthy Adults

The current voriconazole dosing recommendation in adolescents is based on limited efficacy and pharmacokinetic data. To confirm the appropriateness of dosing adolescents like adults, a pharmacokinetic study was conducted in 26 immunocompromised adolescents aged 12 to <17 years following intraveno...

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Autori principali: Driscoll, Timothy A., Frangoul, Haydar, Nemecek, Eneida R., Murphey, Donald K., Yu, Lolie C., Blumer, Jeffrey, Krance, Robert A., Baruch, Alice, Liu, Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232803/
https://ncbi.nlm.nih.gov/pubmed/21911570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05010-11
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