Anti-Inflammatory Effects of Moxifloxacin on Activated Human Monocytic Cells: Inhibition of NF-κB and Mitogen-Activated Protein Kinase Activation and of Synthesis of Proinflammatory Cytokines

We previously showed that moxifloxacin (MXF) exerts protective anti-inflammatory effects in immunosuppressed mice infected with Candida albicans by inhibiting interleukin-8 (IL-8) and tumor necrosis factor alpha (TNF-α) production in the lung. Immunohistochemistry demonstrated inhibition of nuclear...

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Bibliographic Details
Main Authors: Weiss, Taly, Shalit, Itamar, Blau, Hannah, Werber, Sara, Halperin, Drora, Levitov, Avital, Fabian, Ina
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
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Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC415605/
https://ncbi.nlm.nih.gov/pubmed/15155187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.1974-1982.2004
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