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Mitogen-Activated Protein Kinase Phosphatase 1 Disrupts Proinflammatory Protein Synthesis in Endotoxin-Adapted Monocytes

Autotoxic production of proinflammatory mediators during early sepsis induces excessive inflammation, and their later suppression may limit the immune response. We previously reported that sepsis differentially represses transcription and translation of tumor necrosis factor alpha (TNF-α) and interl...

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Detalhes bibliográficos
Main Authors: Brudecki, Laura, Ferguson, Donald A., McCall, Charles E., El Gazzar, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889586/
https://ncbi.nlm.nih.gov/pubmed/23825193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00264-13
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