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Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes.

After the introduction of mitochondria with a mixture of mutant and wild-type mitochondrial DNA (mtDNA) into a human rho degree cell line (143B.206), Yoneda et al. [Yoneda, M., Chomyn, A., Martinuzzi, A., Hurko, O. & Attardi, G. (1992) Proc. Natl. Acad. Sci. USA 89, 11164-11168] observed a shift in...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Dunbar, D R, Moonie, P A, Jacobs, H T, Holt, I J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41558/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7604033/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.14.6562
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