Novel Pharmacokinetic-Pharmacodynamic Model for Prediction of Outcomes with an Extended-Release Formulation of Ciprofloxacin

The pharmacokinetics of an extended-release (XR) formulation of ciprofloxacin has been compared to that of the immediate-release (IR) product in healthy volunteers. The only significant difference in pharmacokinetic parameters between the two formulations was seen in the rate constant of absorption,...

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Bibliographic Details
Main Authors: Meagher, Alison K., Forrest, Alan, Dalhoff, Axel, Stass, Heino, Schentag, Jerome J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC415574/
https://ncbi.nlm.nih.gov/pubmed/15155200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2061-2068.2004
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