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The Balanced Regulation of Hsc70 by DNJ-13 and UNC-23 Is Required for Muscle Functionality

The molecular chaperone Hsc70 assists in the folding of non-native proteins together with its J domain- and BAG domain-containing cofactors. In Caenorhabditis elegans, two BAG domain-containing proteins can be identified, one of them being UNC-23, whose mutation induces severe motility dysfunctions....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Papsdorf, Katharina, Sacherl, Julia, Richter, Klaus
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155687/
https://ncbi.nlm.nih.gov/pubmed/25053410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.565234
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