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Hsc70 is required for endocytosis and clathrin function in Drosophila

By screening for Drosophila mutants exhibiting aberrant bride of sevenless (Boss) staining patterns on eye imaginal disc epithelia, we have recovered a point mutation in Hsc70-4, the closest homologue to bovine clathrin uncoating ATPase. Although the mutant allele was lethal, analysis of mutant clon...

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Detalhes bibliográficos
Main Authors: Chang, Henry C., Newmyer, Sherri L., Hull, Michael J., Ebersold, Melanie, Schmid, Sandra L., Mellman, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173062/
https://ncbi.nlm.nih.gov/pubmed/12427870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200205086
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