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FamLBL: detecting rare haplotype disease association based on common SNPs using case-parent triads

Motivation: In recent years, there has been an increasing interest in using common single-nucleotide polymorphisms (SNPs) amassed in genome-wide association studies to investigate rare haplotype effects on complex diseases. Evidence has suggested that rare haplotypes may tag rare causal single-nucle...

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Hlavní autoři: Wang, Meng, Lin, Shili
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155250/
https://ncbi.nlm.nih.gov/pubmed/24849576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu347
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