Early Diagnosis of Orthopedic Implant Failure Using Macromolecular Imaging Agents

PURPOSE: To develop and evaluate diagnostic tools for early detection of wear particle-induced orthopaedic implant loosening. METHODS: N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer was tagged with an near infrared dye and used to detect the inflammation induced by polymethylmethacrylate (PMMA)...

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Main Authors: Ren, Ke, Dusad, Anand, Zhang, Yijia, Purdue, P. Edward, Fehringer, Edward V., Garvin, Kevin L., Goldring, Steven R., Wang, Dong
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155031/
https://ncbi.nlm.nih.gov/pubmed/24590878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1310-x
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