Simvastatin Prodrug Micelles Target Fracture and Improve Healing

Simvastatin (SIM), a widely used anti-lipidaemic drug, has been identified as a bone anabolic agent. Its poor water solubility and the lack of distribution to the skeleton, however, have limited its application in the treatment of bone metabolic diseases. In this study, an amphiphilic macromolecular...

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發表在:J Control Release
Main Authors: Jia, Zhenshan, Zhang, Yijia, Chen, Yen Hsun, Dusad, Anand, Yuan, Hongjiang, Ren, Ke, Li, Fei, Fehringer, Edward V., Purdue, P. Edward, Goldring, Steven R., Daluiski, Aaron, Wang, Dong
格式: Artigo
語言:Inglês
出版: 2014
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315241/
https://ncbi.nlm.nih.gov/pubmed/25542644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.12.028
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