Therapeutic Priority of the PI3K/AKT/mTOR Pathway in Small Cell Lung Cancers as Revealed by a Comprehensive Genomic Analysis

INTRODUCTION: The information regarding therapeutically relevant genomic alterations in small cell lung cancer (SCLC) is not well developed. We analyzed the SCLC genome using an integrative approach to stratify the targetable alterations. METHODS: We performed whole exon sequencing (n = 51) and copy...

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Autors principals: Umemura, Shigeki, Mimaki, Sachiyo, Makinoshima, Hideki, Tada, Satoshi, Ishii, Genichiro, Ohmatsu, Hironobu, Niho, Seiji, Yoh, Kiyotaka, Matsumoto, Shingo, Takahashi, Akiko, Morise, Masahiro, Nakamura, Yuka, Ochiai, Atsushi, Nagai, Kanji, Iwakawa, Reika, Kohno, Takashi, Yokota, Jun, Ohe, Yuichiro, Esumi, Hiroyasu, Tsuchihara, Katsuya, Goto, Koichi
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2014
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154841/
https://ncbi.nlm.nih.gov/pubmed/25122428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000250
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