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Identification of a lung adenocarcinoma cell line with CCDC6‐RET fusion gene and the effect of RET inhibitors in vitro and in vivo

Rearrangements of the proto‐oncogene RET are newly identified potential driver mutations in lung adenocarcinoma (LAD). However, the absence of cell lines harboring RET fusion genes has hampered the investigation of the biological relevance of RET and the development of RET‐targeted therapy. Thus, we...

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Bibliografski detalji
Izdano u:Cancer Sci
Glavni autori: Suzuki, Makito, Makinoshima, Hideki, Matsumoto, Shingo, Suzuki, Ayako, Mimaki, Sachiyo, Matsushima, Koutatsu, Yoh, Kiyotaka, Goto, Koichi, Suzuki, Yutaka, Ishii, Genichiro, Ochiai, Atsushi, Tsuta, Koji, Shibata, Tatsuhiro, Kohno, Takashi, Esumi, Hiroyasu, Tsuchihara, Katsuya
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657251/
https://ncbi.nlm.nih.gov/pubmed/23578175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12175
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