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Identification of a lung adenocarcinoma cell line with CCDC6‐RET fusion gene and the effect of RET inhibitors in vitro and in vivo

Rearrangements of the proto‐oncogene RET are newly identified potential driver mutations in lung adenocarcinoma (LAD). However, the absence of cell lines harboring RET fusion genes has hampered the investigation of the biological relevance of RET and the development of RET‐targeted therapy. Thus, we...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Suzuki, Makito, Makinoshima, Hideki, Matsumoto, Shingo, Suzuki, Ayako, Mimaki, Sachiyo, Matsushima, Koutatsu, Yoh, Kiyotaka, Goto, Koichi, Suzuki, Yutaka, Ishii, Genichiro, Ochiai, Atsushi, Tsuta, Koji, Shibata, Tatsuhiro, Kohno, Takashi, Esumi, Hiroyasu, Tsuchihara, Katsuya
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657251/
https://ncbi.nlm.nih.gov/pubmed/23578175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12175
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