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Identification of a lung adenocarcinoma cell line with CCDC6‐RET fusion gene and the effect of RET inhibitors in vitro and in vivo

Rearrangements of the proto‐oncogene RET are newly identified potential driver mutations in lung adenocarcinoma (LAD). However, the absence of cell lines harboring RET fusion genes has hampered the investigation of the biological relevance of RET and the development of RET‐targeted therapy. Thus, we...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Suzuki, Makito, Makinoshima, Hideki, Matsumoto, Shingo, Suzuki, Ayako, Mimaki, Sachiyo, Matsushima, Koutatsu, Yoh, Kiyotaka, Goto, Koichi, Suzuki, Yutaka, Ishii, Genichiro, Ochiai, Atsushi, Tsuta, Koji, Shibata, Tatsuhiro, Kohno, Takashi, Esumi, Hiroyasu, Tsuchihara, Katsuya
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657251/
https://ncbi.nlm.nih.gov/pubmed/23578175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12175
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