Illumina TruSeq Synthetic Long-Reads Empower De Novo Assembly and Resolve Complex, Highly-Repetitive Transposable Elements

High-throughput DNA sequencing technologies have revolutionized genomic analysis, including the de novo assembly of whole genomes. Nevertheless, assembly of complex genomes remains challenging, in part due to the presence of dispersed repeats which introduce ambiguity during genome reconstruction. T...

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Main Authors: McCoy, Rajiv C., Taylor, Ryan W., Blauwkamp, Timothy A., Kelley, Joanna L., Kertesz, Michael, Pushkarev, Dmitry, Petrov, Dmitri A., Fiston-Lavier, Anna-Sophie
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154752/
https://ncbi.nlm.nih.gov/pubmed/25188499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106689
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