Zyklophin, a short-acting kappa opioid antagonist, induces scratching in mice

It has been shown previously that norbinaltorphimine (norBNI) and 5΄-guanidinonaltrindole (5΄-GNTI), long-acting kappa opioid receptor (KOPR) antagonists, cause frenzied scratching in mice [1;2]. In the current study, we examined if zyklophin, a short-acting cyclic peptide KOPR antagonist, also elic...

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Bibliographic Details
Main Authors: DiMattio, K.M., Yakovleva, T.V., Aldrich, J.V., Cowan, A., Liu-Chen, L.Y.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154496/
https://ncbi.nlm.nih.gov/pubmed/24503508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.01.022
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