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Down-Regulation of miR-21 Biogenesis by Estrogen Action Contributes to Osteoclastic Apoptosis

Estrogen inhibits osteoclastogenesis and induces osteoclastic apoptosis; however, the molecular mechanisms remain controversial. Recently, a group has demonstrated that osteoclasts are a direct target for estrogen because estrogen stimulates transcription of the Fas Ligand (FasL) gene in osteoclasts...

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Bibliografiske detaljer
Main Authors: Sugatani, Toshifumi, Hruska, Keith A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154486/
https://ncbi.nlm.nih.gov/pubmed/23238785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24471
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