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lncRNA GAS5 Is Upregulated in Osteoporosis and Downregulates miR-21 to Promote Apoptosis of Osteoclasts

BACKGROUND: It has been reported that lncRNA growth arrest-specific transcript 5 (GAS5) interacts with miR-21, which plays critical roles in osteoporosis. The involvement of GAS5 in osteoporosis was investigated in this study. METHODS: Expression levels of GAS5 and miR-21 in plasma of both osteoporo...

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Detalhes bibliográficos
Publicado no:Clin Interv Aging
Main Authors: Cong, Chunlei, Tian, Jun, Gao, Tianqi, Zhou, Changlin, Wang, Yuxiang, Cui, Xintao, Zhu, Liyu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371557/
https://ncbi.nlm.nih.gov/pubmed/32764903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S235197
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