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Impaired Micro-RNA Pathways Diminish Osteoclast Differentiation and Function

Micro-RNAs (miRNAs) are important in regulating cell fate determination because many of their target mRNA transcripts are engaged in cell proliferation, differentiation, and apoptosis. DGCR8, Dicer, and Ago2 are essential factors for miRNA homeostasis. Here we show that these three factors have crit...

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Detalhes bibliográficos
Main Authors: Sugatani, Toshifumi, Hruska, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640963/
https://ncbi.nlm.nih.gov/pubmed/19059913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805777200
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