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Impaired Micro-RNA Pathways Diminish Osteoclast Differentiation and Function
Micro-RNAs (miRNAs) are important in regulating cell fate determination because many of their target mRNA transcripts are engaged in cell proliferation, differentiation, and apoptosis. DGCR8, Dicer, and Ago2 are essential factors for miRNA homeostasis. Here we show that these three factors have crit...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2640963/ https://ncbi.nlm.nih.gov/pubmed/19059913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805777200 |
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