Smurf2 E3 ubiquitin ligase modulates proliferation and invasiveness of breast cancer cells in a CNKSR2 dependent manner

BACKGROUND: Smurf2 is a member of the HECT family of E3 ubiquitin ligases that play important roles in determining the competence of cells to respond to TGF- β/BMP signaling pathway. However, besides TGF-β/BMP pathway, Smurf2 regulates a repertoire of other signaling pathways ranging from planar cel...

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Detalhes bibliográficos
Main Authors: David, Diana, Jagadeeshan, Sankar, Hariharan, Ramkumar, Nair, Asha Sivakumari, Pillai, Radhakrishna Madhavan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154384/
https://ncbi.nlm.nih.gov/pubmed/25191523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-9-2
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