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Therapeutic strategies impacting cancer cell glutamine metabolism

The metabolic adaptations that support oncogenic growth can also render cancer cells dependent on certain nutrients. Along with the Warburg effect, increased utilization of glutamine is one of the metabolic hallmarks of the transformed state. Glutamine catabolism is positively regulated by multiple...

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Библиографические подробности
Главные авторы: Lukey, Michael J, Wilson, Kristin F, Cerione, Richard A
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154374/
https://ncbi.nlm.nih.gov/pubmed/24047273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.130
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