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Therapeutic strategies impacting cancer cell glutamine metabolism

The metabolic adaptations that support oncogenic growth can also render cancer cells dependent on certain nutrients. Along with the Warburg effect, increased utilization of glutamine is one of the metabolic hallmarks of the transformed state. Glutamine catabolism is positively regulated by multiple...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lukey, Michael J, Wilson, Kristin F, Cerione, Richard A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154374/
https://ncbi.nlm.nih.gov/pubmed/24047273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.130
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