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Therapeutic strategies impacting cancer cell glutamine metabolism

The metabolic adaptations that support oncogenic growth can also render cancer cells dependent on certain nutrients. Along with the Warburg effect, increased utilization of glutamine is one of the metabolic hallmarks of the transformed state. Glutamine catabolism is positively regulated by multiple...

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Bibliografiske detaljer
Main Authors: Lukey, Michael J, Wilson, Kristin F, Cerione, Richard A
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154374/
https://ncbi.nlm.nih.gov/pubmed/24047273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.130
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