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G-protein stimulatory subunit alpha and Gq/11α G-proteins are both required to maintain quiescent stem-like chondrocytes

Round chondrocytes in the resting zone of the growth plate provide precursors for columnar chondrocytes and have stem-like properties. Here we demonstrate that these stem-like chondrocytes undergo apoptosis in the absence of the receptor (PPR) for parathyroid hormone-related protein. We examine the...

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Detalhes bibliográficos
Main Authors: Chagin, Andrei S., Vuppalapati, Karuna K., Kobayashi, Tatsuya, Guo, Jun, Hirai, Takao, Chen, Min, Offermanns, Stefan, Weinstein, Lee S., Kronenberg, Henry M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154354/
https://ncbi.nlm.nih.gov/pubmed/24781502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4673
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